The Role of Microbiome Metabolites Review Writing – Medical Science Assignment Help

Assignment Task

Task

Background:

Short chain fatty acids (SCFAs), predominantly, acetate, propionate and butyrate are produced by microorganisms that reside as part of the gut microbiome when they ferment carbohydrates and fibres (Maslowski et al 2009, Thorburn et al 2014, Huffnagle 2014). 

Studies showed that these short chain fatty acids are essential for cell function controlling growth. SCFAs can regulate inflammatory responses and there is an emerging evidence that SCFAs can reduce chronic inflammatory gut disorders including ulcerative colitis (Sun et al 2017, Tan et al 2017). Furthermore, we now know that these SCFAs are not restricted to the gut and recent studies showed they can also enter the bloodstream and distant tissues in particular the lungs (Cummings et al 1987). 

Following on from this, there is now evidence proving that these SCFAs in the lungs can protect against infections including COVID19. 

In this review the student is expected to:

1. Analyse the function of short chain fatty acids during different bacterial and viral infections. 

2. Analyse the short chain fatty acids mechanism. 

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