Correlating Chest wall OAR Doses Review Writing – Medical Science Assignment Help

Assignment Task

Task

Brief Description:

Stereotactic Ablative radiotherapy (SABR) is the preferred treatment technique for early stage non-small cell lung cancer. Using this technique, patients are planned to receive either 55Gy in 5 fractions or 60Gy in 8 fractions according to the established protocol. Due to the involved high dose and proximity of the tumour to the normal organs, complications from this technique are not always avoidable. In this retrospective study, chest wall toxicity is to be analysed in detail in co-relation to the predicted dose delivery from the treatment planning process.

Materials and Methods:

In this study, the clinical treatment plans used for 30 Ca. Lung patients treated with SABR treatment technique will be retrospectively analysed to correlate the chest wall dose to the chest pain and rib fractures. All the patients’ dicom RT data will be anonymised using the department’s approved anonymiser program and will be transferred to the ‘training database’ of the Raystation treatment planning system. The evaluation of the volume delineation and dose-volume estimation will be performed using the anonymised data. Delivered dose to the chest wall and its correlation to the chest wall complications will be analysed through suitable radiobiological indicators and that will be compared with the clinical follow-up information for respective patients.

Outcome of the project:

The project outcome may highlight the possibilities to improve the patient preparation, volume rendering for regions of interest in the thoracic region and possibly establish alternative treatment delivery technique strategies if there is a correlation observed between delivered dose and observed complications.

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